Home > April 2007 > The Proverbial Ostrich and its enemy; Autologous Stem Cells

The Proverbial Ostrich and its enemy; Autologous Stem Cells
By Dr. Chuck McGowen

We’ve all heard of the ostrich that hid its head in the sand when ever a natural enemy approached. I am not certain that the analogy necessarily applies completely, but it’s close to what I just read in my March 2007 issue of The American Journal of Medicine, normally clearly up on the latest regarding the state of the art in the world of medicine and affectionately known to internists as “The Green Journal.” However in this case they have totally ignored the most exciting research in that alleged “state of the art” commentary.

The article of note in that most recent issue is entitled “Office Management of Geriatric Urinary Incontinence.” In simple terms geriatric incontinence relates to persons past 65 who have lost their ability to control their urinary bladders; they spill urine into their underwear or beds with the slightest of provocations. A truly distressing, embarrassing and quality of life altering problem.

The clinical piece points out several pertinent statistics. Women are affected 2 to 3 times as often as men, basically due to anatomical differences in the urethra. 15% to 30% of those persons 65 years of age and older are affected; a formidable number. The cost of treating the condition in the US in the year 2000 approached a staggering $20 billion.

The treatise discussed various treatment options, citing behavioral changes, drug treatment, permanent catheter placement, reconstructive surgery, artificial sphincters and injections with bulk agents (mostly collagen). What was conspicuous by its absence was the newly reported research coming out of Austria and reported in the December 13, 2006 Issue of Internal Medicine News (Also reported in this blog on 1-7-07) that has to have all informed physicians reeling with excitement. Those researchers were profoundly successful in their treatment of this most troubling condition of urinary incontinence.

They first harvested stem cells (autologous) from the forearm muscles of 63 incontinent patients. They then cultured those stem cells and produced 50 million myoblasts (muscle cell precursors) and 50 million fibroblasts (connective tissue cell precursors). The Austrian physicians then injected the former into the region of the inefficient bladder sphincter muscles and the latter into the sub mucosal regions of the urethra. After 6 to 30 months of follow up 79% of those person so treated were entirely continent. They could pitch their Depends@ into the trash. Of those 28 patients treated in the good old American way, that is with collagen injections, only 2 (7%) were relieved of their incontinence. Because the stem cells were derived from their own bodies, rejection of the grafts was never an issue.

When are the researchers in these United States ever going to stop chasing after the money and legislation to support Embryonic Stem Cell (ESC) research when autologous stem cell transplantations have proven to be so successful? It appears that the ESC ostrich is afraid of losing his money because the big bad wolf, the autologous stem cell out of Austria, is sneaking up behind.

Monday, April 02, 2007, 08:39 AM

Email to a Friend  |  Printer Friendly Page  |  Permalink

Bookmark and Share

Dr. Charles McGowen's Bio


Past Posts

What is scientifically natural about same sex marriage? Nothing!
How does diabetes relate to pancreatic cancer? Don’t ask your attorney.
It is time for Washington to take off the blinders and take notice of what really works in Stem Cell therapy
The Pathophysiology of Christ’s Death
Soda Pop May Be Doing More Than Just Adding Calories
The Proof is not to be found in the Pudding

June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
October 2006
September 2006
August 2006
July 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005

Search this blog: